October 29, 2019American Museum of Natural History LeFrak Theater Central Park West at 79th St, New York, NY 10024      Keynote Speaker: David Reich, PhD, Harvard University  Conference Leaders/Moderators: George Amato, PhD, American Museum of Natural History Jean-Laurent Casanova, MD, PhD, Rockefeller University & HHMI Bruce D. Gelb, MD, Icahn School of Medicine at Mount Sinai David Goldstein, PhD, Columbia University Cheryl Y. Hayashi, PhD, American Museum of Natural History   Conference Schedule: 8:00 am - 8:30 am Registration and Continental Breakfast 8:30 am - 8:45 am IntroductionsJean-Laurent Casanova, MD, PhDInvestigator, HHMI & Professor, The Rockefeller UniversityCheryl Hayashi, PhDSackler Institute for Comparative Genomics, American Museum of Natural History 8:45 am - 9:45 am Session 1: Keynote Seminar Moderator: David Goldstein, PhD   David Reich, PhDHarvard UniversityAncient DNA and the New Science of the Human Past 9:45 am - 10:15 am Break and Posters 10:15 am - 11:35 am Session 2: Contributed Presentations in Medical Genomics Moderator: Bruce Gelb, MD 10:15 am - 10:35 am Orrin Devinsky, MDNew York UniversityMolecular basis of epilepsies 10:35 am - 10:55 am Andrew Allen, PhDDuke UniversityUsing standing variation to assess pathogenicity 10:55 am - 11:15 am Christopher Park, PhDFlatiron Institute, Simons FoundationWhole-genome analysis identifies contribution of noncoding mutations to autism risk 11:15 am - 11:35 am Joseph Buxbaum, PhDIcahn School of Medicine at Mount SinaiGenetics of autism 11:35 am - 1:00 pm Lunch and Posters in the Milstein Hall of Ocean Life 1:00 pm - 2:40 pm Session 3: Contributed Presentations in Evolution and Population Genomics, Part IModerator: Susan Perkins, PhD, American Museum of Natural History 1:00 pm - 1:20 pm Robert Burk, MDAlbert Einstein College of MedicineHuman papillomavirus evolution and carcinogenesis   1:20 pm - 1:40 pm Bluma Lesch, MD, PhDYale School of MedicineEvolution of epigenetic poising in the mammalian germ